HDAC2 antibody

Product Name HDAC2 antibody

Catalog No PAab09976

Packing 100ul

Form liquid

Alternative Name HD2, HDAC2, histone deacetylase 2, RPD3, YAF1

Purification Immunogen affinity purified

Purity 95% as determined by SDS-PAGE

Host Rabbit

Isotype IgG

Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)

Background/ FUNCTION

This gene product belongs to the histone deacetylase family. Histone deacetylases act via the formation of large multiprotein complexes, and are responsible for the deacetylation of lysine residues at the N-terminal regions of core histones (H2A, H2B, H3 and H4). This protein forms transcriptional repressor complexes by associating with many different proteins, including YY1, a mammalian zinc-finger transcription factor. Thus, it plays an important role in transcriptional regulation, cell cycle progression and developmental events. Alternative splicing results in multiple transcript variants.

Immunogen histone deacetylase 2

Specificity Human

Tested Application ELISA, WB, IHC

Recommended dilution WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

IHC use Immunohistochemistry of paraffin-embedded human intestinal cancer using PAab09976(HDAC2 antibody) at dilution of 1:100

WB use

293T cells were subjected to SDS PAGE followed by western blot with PAab09976(HDAC2 antibody) at dilution of 1:1000

Protein Information

Gene ID 3066

Uniprot ID Q92769

Calculated MW 56 kDa

Research Area Epigenetics, Cardiovascular, Metabolism