SOD1 antibody

Product Name SOD1 antibody

Catalog No PAab09989

Packing 100ul

Form liquid

Alternative Name Superoxide dismutase [Cu-Zn],Superoxide dismutase 1,hSod1

Purification Immunogen affinity purified

Purity 95% as determined by SDS-PAGE

Host Rabbit

Isotype IgG

Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)

Background/ FUNCTION

Superoxide dismutase 1, soluble(amyotrophic lateral sclerosis 1(adult))(SOD1, synonyms: ALS, SOD, ALS1, IPOA) binds copper and zinc ions and is one of two isozymes responsible for destroying free uperoxide radicals in the body. This isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis.

Immunogen superoxide dismutase 1, soluble

Specificity Human, Mouse, Rat

Tested Application ELISA, WB, IHC

Recommended dilution WB: 1:500-1:2000; IHC: 1:50-1:500

IHC use Immunohistochemistry of paraffin-embedded human liver cancer tissue slide using PAab09989(SOD1 Antibody) at dilution of 1:200

WB use

HEK-293 cells were subjected to SDS PAGE followed by western blot with PAab09989(SOD1 antibody) at dilution of 1:1000

Protein Information

Gene ID 6647

Uniprot ID P00441

Calculated MW 16 kDa

Research Area Neuroscience, Metabolism