TRAF1 antibody

Product Name TRAF1 antibody

Catalog No PAab10063

Packing 100ul

Form liquid

Alternative Name EBI6, TRAF1

Purification Immunogen affinity purified

Purity 95% as determined by SDS-PAGE

Host Rabbit

Isotype IgG

Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)

Background/ FUNCTION

Adapter molecule that regulates the activation of NF-kappa-B and JNK. Plays a role in the regulation of cell survival and apoptosis. The heterotrimer formed by TRAF1 and TRAF2 is part of a E3 ubiquitin-protein ligase complex that promotes ubiquitination of target proteins, such as MAP3K14. The TRAF1/TRAF2 complex recruits the antiapoptotic E3 protein-ubiquitin ligases BIRC2 and BIRC3 to TNFRSF1B/TNFR2.

Immunogen TNF receptor-associated factor 1

Specificity Human

Tested Application ELISA, IHC

Recommended dilution IHC: 1:20-1:200

IHC use Immunohistochemistry of paraffin-embedded human colon cancer tissue slide using PAab10063(TRAF1 Antibody) at dilution of 1:200

WB use

Protein Information

Gene ID 26146

Uniprot ID Q13077

Calculated MW 46 kDa

Research Area Immunology, Signal Transduction, Metabolism