Anti-FOLR1 antibody
Product Name Anti-FOLR1 antibody
Catalog No PAab03184
Packing 100ug
Form liquid
Alternative Name FOLR
Purification Immunogen affinity purified
Purity 95% as determined by SDS-PAGE
Host Rabbit
Isotype IgG
Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)
Background/ FUNCTION
Binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate and folate analogs into the interior of cells. Has high affinity for folate and folic acid analogs at neutral pH. Exposure to slightly acidic pH after receptor endocytosis triggers a conformation change that strongly reduces its affinity for folates and mediates their release. Required for normal embryonic development and normal cell proliferation.
Immunogen folate receptor 1 (adult)
Specificity Human
Tested Application ELISA,WB,IF
Recommended dilution
IHC use
WB use
Protein Information
Gene ID2348
Uniprot ID P15328
Calculated MW
location
Technical Principle & Methodology
The quality assurance and experimental performance of this biological reagent are rigorously optimized and standardized according to its specific technical pathway:
Immunoglobulin Enzyme Conjugation and Signal Amplification Cascade
(免疫球蛋白酶标偶联与分子信号级联放大技术). This ensures maximum reproducibility across clinical research and scientific workflows.
