Anti-Visfatin antibody

Product Information

Product Name: Anti-Visfatin antibody

Catalog No.: LSMab09847

Packing: 100ug

Form: liquid

Purity:more than 95% as determined by SDS-PAGE

Purification: protein A+G purified

Host: Mouse

Isotype: IgG2b

Storage Condition: PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20degrees for 24 months(Avoid repeated freeze / thaw cycles.)

Immunogen Information

Immunogen Name:nicotinamide phosphoribosyltransferase

Background: Nicotinamide phosphoribosyltransferase(NAMPT) has two usual synonyms termed Visfatin and PBEF. Its primary role is to catalyze the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, an intermediate in the biosynthesis of NAD, which is the rate limiting component in the mammalian NAD biosynthesis pathway. NAMPT is localized in cytoplasm and expressed in large amounts in bone marrow, liver tissue, and muscle tissues. NAMPT inhibits neutrophil apoptosis in experimental inflammation and clinical sepsis. NAMPT levels are altered in plasma of patients with type 2 diabetes mellitus(T2DM), and it is now evidenced that NAMPT may plays a role in lipid metabolism.

Synonyms: 1110035O14Rik, DKFZp666B131, NAmPRTase, NAMPT, PBEF, PBEF1, Pre B cell enhancing factor, VF, VISFATIN

Calculated MW:

Uniprot ID: P43490

Gene ID: 10135

Validation

Specificity: Human, Mouse, Rat

Tested Application: ELISA, WB, IHC, IF

Recommended dilution: WB: 1:1000-1:4000; IHC: 1:50-1:500; IF: 1:50-1:500

IHC use: Immunohistochemistry of paraffin-embedded human breast cancer tissue slide using LSMab09847( Visfatin antibody ) at dilution of 1:200

WB use: rat heart tissue were subjected to SDS PAGE followed by western blot with LSMab09847( Visfatin antibody ) at dilution of 1:2000

Caution:

1. Product is used for research only!