Anti-ACPP antibody

Product Name Anti-ACPP antibody

Catalog No PAab00102

Packing 100ug

Form liquid

Alternative Name Acid phosphatase antibody, prostate antibody, ACP 3 antibody, ACP3 antibody, ACPP antibody, PAP antibody, Prostatic acid phosphatase

Purification Protein A+G purification

Purity 95% as determined by SDS-PAGE

Host Mouse

Isotype IgG2a

Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)

Background/ FUNCTION

A non-specific tyrosine phosphatase that dephosphorylates a diverse number of substrates under acidic conditions (pH 4-6) including alkyl, aryl, and acyl orthophosphate monoesters and phosphorylated proteins. Has lipid phosphatase activity and inactivates lysophosphatidic acid in seminal plasma. Isoform 2: the cellular form also has ecto-5'- nucleotidase activity in dorsal root ganglion (DRG) neurons. Generates adenosine from AMP which acts as a pain suppressor. Acts as a tumor suppressor of prostate cancer through dephosphorylation of ERBB2 and deactivation of MAPK-mediated signaling.

Immunogen acid phosphatase, prostate

Specificity Human

Tested Application ELISA,WB,IHC

Recommended dilution WB :1:200-1:2000;IHC:1:20-1:200

IHC use

Immunohistochemistry of paraffin-embedded human prostate hyperplasia usingACPP antibody at dilution of 1:50

WB use

human testis tissue were subjected to SDS PAGE followed by western blot with PAab00102(ACPP antibody) at dilution of 1:400

Protein Information

Gene ID55

Uniprot ID P15309

Calculated MW 48kDa

location