Anti-ADIPOQ antibody

Product Name Anti-ADIPOQ antibody

Catalog No PAab00170

Packing 100ug

Form liquid

Alternative Name ACDC antibody, ACRP30 antibody, adiponectin antibody, ADIPOQ antibody, ADIPQTL1 antibody, ADPN antibody, APM 1 antibody, APM1 antibody, GBP28 antibody, Gelatin binding protein

Purification Protein A+G purification

Purity 95% as determined by SDS-PAGE

Host Mouse

Isotype IgG2a

Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)

Background/ FUNCTION

Important adipokine involved in the control of fat metabolism and insulin sensitivity, with direct anti-diabetic, anti-atherogenic and anti-inflammatory activities. Stimulates AMPK phosphorylation and activation in the liver and the skeletal muscle, enhancing glucose utilization and fatty-acid combustion. Antagonizes TNF-alpha by negatively regulating its expression in various tissues such as liver and macrophages, and also by counteracting its effects. Inhibits endothelial NF-kappa-B signaling through a cAMP-dependent pathway. May play a role in cell growth, angiogenesis and tissue remodeling by binding and sequestering various growth factors with distinct binding affinities, depending on the type of complex, LMW, MMW or HMW.

Immunogen adiponectin, C1Q and collagen domain containing

Specificity Human

Tested Application ELISA,WB

Recommended dilution WB :1:500-1:5000

IHC use

WB use

human adipose tissue were subjected to SDS PAGE followed by western blot with PAab00170( ADIPOQ Antibody) at dilution of 1:1000

Protein Information

Gene ID9370

Uniprot ID Q15848

Calculated MW 26kDa

location