Anti-AICDA antibody

Product Name Anti-AICDA antibody

Catalog No PAab00233

Packing 100ug

Form liquid

Alternative Name AICDA antibody, AID antibody, ARP2 antibody, CDA2 antibody, Cytidine aminohydrolase antibody, HIGM2

Purification Immunogen affinity purified

Purity 95% as determined by SDS-PAGE

Host Rabbit

Isotype IgG

Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)

Background/ FUNCTION

Single-stranded DNA-specific cytidine deaminase. Involved in somatic hypermutation, gene conversion, and class- switch recombination in B-lymphocytes. Required for several crucial steps of B-cell terminal differentiation necessary for efficient antibody responses. May also play a role in the epigenetic regulation of gene expression by participating in DNA demethylation.

Immunogen activation-induced cytidine deaminase

Specificity Human,Mouse ,Rat

Tested Application ELISA,WB

Recommended dilution WB :1:200-1:2000

IHC use

WB use

Jurkat cells were subjected to SDS PAGE followed by western blot with PAab00233(AID antibody) at dilution of 1:800

Protein Information

Gene ID57379

Uniprot ID Q9GZX7

Calculated MW 24kDa,observed 50kDa

location