Anti-ATG4B antibody
Product Name Anti-ATG4B antibody
Catalog No PAab00674
Packing 100ug
Form liquid
Alternative Name APG4B antibody, AUTL1 antibody, KIAA0943
Purification Immunogen affinity purified
Purity 95% as determined by SDS-PAGE
Host Rabbit
Isotype IgG
Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)
Background/ FUNCTION
Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3, GABARAPL1, GABARAPL2 and GABARAP, to reveal a C-terminal glycine. Exposure of the glycine at the C- terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy. Has also an activity of delipidating enzyme for the PE-conjugated forms.
Immunogen ATG4 autophagy related 4 homolog B (S. cerevisiae)
Specificity Human,Mouse ,Rat
Tested Application ELISA,WB,IHC,IP
Recommended dilution
IHC use
Immunohistochemistry of paraffin-embedded human pancreas cancer usingATG4B antibody at dilution of 1:50
WB use
human brain tissue were subjected to SDS PAGE followed by western blot with PAab00674(ATG4B antibody) at dilution of 1:800
Protein Information
Gene ID23192
Uniprot ID Q9Y4P1
Calculated MW
location