Anti-ATPIF1 antibody

Product Name Anti-ATPIF1 antibody

Catalog No PAab00735

Packing 100ug

Form liquid

Alternative Name ATPI

Purification Immunogen affinity purified

Purity 95% as determined by SDS-PAGE

Host Rabbit

Isotype IgG

Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)

Background/ FUNCTION

Endogenous F(1)F(o)-ATPase inhibitor limiting ATP depletion when the mitochondrial membrane potential falls below a threshold and the F(1)F(o)-ATP synthase starts hydrolyzing ATP to pump protons out of the mitochondrial matrix. Required to avoid the consumption of cellular ATP when the F(1)F(o)-ATP synthase enzyme acts as an ATP hydrolase. Indirectly acts as a regulator of heme synthesis in erythroid tissues: regulates heme synthesis by modulating the mitochondrial pH and redox potential, allowing FECH to efficiently catalyze the incorporation of iron into protoporphyrin IX to produce heme.

Immunogen ATPase inhibitory factor 1

Specificity Human, Mouse

Tested Application ELISA,WB

Recommended dilution

IHC use

WB use

Protein Information

Gene ID93974

Uniprot ID Q9UII2

Calculated MW

location