Anti-BACE1 antibody

Product Name Anti-BACE1 antibody

Catalog No PAab00781

Packing 100ug

Form liquid

Alternative Name BACE antibody, KIAA1149

Purification Immunogen affinity purified

Purity 95% as determined by SDS-PAGE

Host Rabbit

Isotype IgG

Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)

Background/ FUNCTION

Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase.

Immunogen beta-site APP-cleaving enzyme 1

Specificity Human, Mouse , Zebrafish

Tested Application ELISA,WB,IP,IHC

Recommended dilution

IHC use

Immunohistochemistry of paraffin-embedded mouse brain tissue slide using BACE1 Antibody at dilution of 1:200 heat mediated antigen retrieved with Tris-EDTA bufferpH9).

WB use

mouse brain tissue were subjected to SDS PAGE followed by western blot with PAab00781(BACE1 antibody) at dilution of 1:500

Protein Information

Gene ID23621

Uniprot ID P56817

Calculated MW

location