Anti-BAX antibody

Product Name Anti-BAX antibody

Catalog No PAab00810

Packing 100ug

Form liquid

Alternative Name BCL2L4

Purification Immunogen affinity purified

Purity 95% as determined by SDS-PAGE

Host Rabbit

Isotype IgG

Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)

Background/ FUNCTION

Accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis.

Immunogen BCL2-associated X protein

Specificity Human, Mouse ,Rat

Tested Application ELISA,WB,IHC,IP,FC,IF

Recommended dilution

IHC use

Immunohistochemistry of paraffin-embedded human kidney tissue slide using BAX Antibody at dilution of 1:50

WB use

HEK-293 cells were subjected to SDS PAGE followed by western blot with PAab00810(BAX antibody) at dilution of 1:1000

Protein Information

Gene ID581

Uniprot ID Q07812

Calculated MW

location