Anti-BMI1 antibody

Product Name Anti-BMI1 antibody

Catalog No PAab00913

Packing 100ug

Form liquid

Alternative Name PCGF4 antibody, RNF51

Purification Immunogen affinity purified

Purity 95% as determined by SDS-PAGE

Host Rabbit

Isotype IgG

Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)

Background/ FUNCTION

Component of a Polycomb group (PcG) multiprotein PRC1- like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. In the PRC1 complex, it is required to stimulate the E3 ubiquitin-protein ligase activity of RNF2/RING2.

Immunogen BMI1 polycomb ring finger oncogene

Specificity Human, Mouse

Tested Application ELISA,WB,IHC,IF,IP

Recommended dilution

IHC use

Immunohistochemistry of paraffin-embedded human liver cancer usingBMI1 antibody at dilution of 1:50

WB use

U-937 cells were subjected to SDS PAGE followed by western blot with PAab00913(BMI1 antibody) at dilution of 1:1000

Protein Information

Gene ID648

Uniprot ID P35226

Calculated MW

location