Anti-BMP2 antibody

Product Name Anti-BMP2 antibody

Catalog No PAab00917

Packing 100ug

Form liquid

Alternative Name BMP2A

Purification Immunogen affinity purified

Purity 95% as determined by SDS-PAGE

Host Rabbit

Isotype IgG

Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)

Background/ FUNCTION

Induces cartilage and bone formation (PubMed:3201241). Stimulates the differentiation of myoblasts into osteoblasts via the EIF2AK3-EIF2A- ATF4 pathway. BMP2 activation of EIF2AK3 stimulates phosphorylation of EIF2A which leads to increased expression of ATF4 which plays a central role in osteoblast differentiation. In addition stimulates TMEM119, which upregulates the expression of ATF4 (PubMed:24362451).

Immunogen bone morphogenetic protein 2

Specificity Human,Mouse ,Rat,Pig

Tested Application ELISA,WB,IHC

Recommended dilution WB: 1:500-1: 5000;IHC: 1:20-1:200;IF: 1:50-1:500

IHC use

Immunohistochemistry of paraffin-embedded human small intestine tissue slide usingBMP2 Antibody at dilution of 1:50 FNab00917

WB use

HeLa cells were subjected to SDS PAGE followed by western blot with PAab00917(BMP2 antibody) at dilution of 1:100

Protein Information

Gene ID650

Uniprot ID P12643

Calculated MW

location