Anti-BMPR2 antibody

Product Name Anti-BMPR2 antibody

Catalog No PAab00924

Packing 100ug

Form liquid

Alternative Name PPH1

Purification Immunogen affinity purified

Purity 95% as determined by SDS-PAGE

Host Rabbit

Isotype IgG

Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)

Background/ FUNCTION

On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Binds to BMP7, BMP2 and, less efficiently, BMP4. Binding is weak but enhanced by the presence of type I receptors for BMPs. Mediates induction of adipogenesis by GDF6.

Immunogen bone morphogenetic protein receptor, type II (serine/threonine kinase)

Specificity Human,Mouse ,Rat

Tested Application ELISA,WB,IP

Recommended dilution

IHC use

WB use

Protein Information

Gene ID659

Uniprot ID Q13873

Calculated MW

location