Anti-DNAJB6 antibody

Product Name Anti-DNAJB6 antibody

Catalog No PAab02452

Packing 100ug

Form liquid

Alternative Name HSJ2 antibody, MRJ antibody, MSJ1

Purification Immunogen affinity purified

Purity 95% as determined by SDS-PAGE

Host Rabbit

Isotype IgG

Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)

Background/ FUNCTION

Plays an indispensable role in the organization of KRT8/KRT18 filaments. Acts as an endogenous molecular chaperone for neuronal proteins including huntingtin. Suppresses aggregation and toxicity of polyglutamine-containing, aggregation-prone proteins. Isoform B but not isoform A inhibits huntingtin aggregation. Has a stimulatory effect on the ATPase activity of HSP70 in a dose-dependent and time-dependent manner and hence acts as a co-chaperone of HSP70. Also reduces cellular toxicity and caspase-3 activity.

Immunogen DnaJ (Hsp40) homolog, subfamily B, member 6

Specificity Human,Mouse ,Rat

Tested Application ELISA,IHC,IF,WB,IP

Recommended dilution

IHC use

Immunohistochemistry of paraffin-embedded human colon cancer usingDNAJB6 antibody at dilution of 1:100

WB use

mouse brain tissue were subjected to SDS PAGE followed by western blot with PAab02452( DNAJB6 Antibody) at dilution of 1:600

Protein Information

Gene ID10049

Uniprot ID O75190

Calculated MW

location