Anti-E2F3 antibody

Product Name Anti-E2F3 antibody

Catalog No PAab02601

Packing 100ug

Form liquid

Alternative Name KIAA0075

Purification Immunogen affinity purified

Purity 95% as determined by SDS-PAGE

Host Rabbit

Isotype IgG

Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)

Background/ FUNCTION

Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC- 3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DRTF1/E2F complex functions in the control of cell-cycle progression from G1 to S phase. E2F3 binds specifically to RB1 in a cell-cycle dependent manner. Inhibits adipogenesis, probably through the repression of CEBPA binding to its target gene promoters (By similarity).

Immunogen E2F transcription factor 3

Specificity Human,Mouse ,Rat

Tested Application ELISA,WB,IP

Recommended dilution

IHC use

WB use

Protein Information

Gene ID1871

Uniprot ID O00716

Calculated MW

location