Anti-GSPT2 antibody
Product Name Anti-GSPT2 antibody
Catalog No PAab03681
Packing 100ug
Form liquid
Alternative Name ERF3B
Purification Immunogen affinity purified
Purity 95% as determined by SDS-PAGE
Host Rabbit
Isotype IgG
Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)
Background/ FUNCTION
Involved in translation termination in response to the termination codons UAA, UAG and UGA. May play a role as a potent stimulator of the release factor activity of ETF1. Exhibits GTPase activity, which is ribosome- and ETF1-dependent. May play a role in cell cycle progression. Component of the transient SURF complex which recruits UPF1 to stalled ribosomes in the context of nonsense-mediated decay (NMD) of mRNAs containing premature stop codons.
Immunogen G1 to S phase transition 2
Specificity Human,Mouse ,Rat
Tested Application ELISA,WB,IHC
Recommended dilution
IHC use
Immunohistochemistry of paraffin-embedded human colon cancer usingGSPT2 antibody at dilution of 1:100
WB use
MCF7 cells were subjected to SDS PAGE followed by western blot with PAab03681(GSPT2 antibody) at dilution of 1:500
Protein Information
Gene ID23708
Uniprot ID Q8IYD1
Calculated MW
location