Anti-IFIT5 antibody
Product Name Anti-IFIT5 antibody
Catalog No PAab04139
Packing 100ug
Form liquid
Alternative Name ISG58 antibody, RI58
Purification Immunogen affinity purified
Purity 95% as determined by SDS-PAGE
Host Rabbit
Isotype IgG
Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)
Background/ FUNCTION
Interferon-induced RNA-binding protein that specifically binds single-stranded RNA bearing a 5'-triphosphate group (PPP- RNA), thereby acting as a sensor of viral single-stranded RNAs. Single-stranded PPP-RNAs, which lack 2'-O-methylation of the 5' cap and bear a 5'-triphosphate group instead, are specific from viruses, providing a molecular signature to distinguish between self and non-self mRNAs by the host during viral infection. Directly binds PPP-RNA in a non-sequence-specific manner. Also recognizes and binds tRNAs.
Immunogen interferon-induced protein with tetratricopeptide repeats 5
Specificity Human
Tested Application ELISA,WB,IHC
Recommended dilution
IHC use
Immunohistochemistry of paraffin-embedded human skin cancer tissue slide using IFIT5 Antibody at dilution of 1:50
WB use
A375 cells were subjected to SDS PAGE followed by western blot with PAab04139(IFIT5 antibody) at dilution of 1:200
Protein Information
Gene ID24138
Uniprot ID Q13325
Calculated MW
location