Anti-IFNAR2 antibody

Product Name Anti-IFNAR2 antibody

Catalog No PAab04148

Packing 100ug

Form liquid

Alternative Name IFNABR antibody, IFNARB

Purification Immunogen affinity purified

Purity 95% as determined by SDS-PAGE

Host Rabbit

Isotype IgG

Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)

Background/ FUNCTION

Associates with IFNAR1 to form the type I interferon receptor. Receptor for interferons alpha and beta. Involved in IFN-mediated STAT1, STAT2 and STAT3 activation (PubMed:26424569). Isoform 1 and isoform 2 are directly involved in signal transduction due to their association with the TYR kinase, JAK1 (PubMed:8181059, PubMed:7665574, PubMed:7759950). Isoform 3 is a potent inhibitor of type I IFN receptor activity (PubMed:7759950).

Immunogen interferon (alpha, beta and omega) receptor 2

Specificity Human

Tested Application ELISA,WB,FC

Recommended dilution

IHC use

WB use

Protein Information

Gene ID3455

Uniprot ID P48551

Calculated MW

location