Anti-Integrin alpha 6X1B-Specific antibody

Product Name Anti-Integrin alpha 6X1B-Specific antibody

Catalog No PAab04342

Packing 100ug

Form liquid

Alternative Name CD49f antibody, DKFZp686J01244 antibody, FLJ18737 antibody, Integrin alpha 6 antibody, integrin antibody, alpha 6 antibody, ITGA6 antibody, ITGA6B antibody, VLA 6

Purification Immunogen affinity purified

Purity 95% as determined by SDS-PAGE

Host Rabbit

Isotype IgG

Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)

Background/ FUNCTION

ITGA6, also named asITGA6B, CD49f and VLA-6, belongs to the integrin alpha chain family. It is a receptor for laminin on platelets. ITGA6 is a receptor for laminin in epithelial cells and it plays a critical structural role in the hemidesmosome. Defects in ITGA6 are a cause of epidermolysis bullosa letalis with pyloric atresia (EB-PA) which also known as junctional epidermolysis bullosa with pyloric atresia (PA-JEB) or aplasia cutis congenita with gastrointestinal atresia. This antibody is specific to isoform Alpha-6X1X2B, isoform Alpha-6X1B and isoform Alpha-6X2B.

Immunogen integrin, alpha 6

Specificity Human,Mouse ,Rat

Tested Application ELISA,WB

Recommended dilution WB:1:500-1:5000

IHC use

WB use

mouse kidney tissue were subjected to SDS PAGE followed by western blot with PAab04342(ITGA6-Specific antibody) at dilution of 1:500

Protein Information

Gene ID

Uniprot ID P23229

Calculated MW 127kDa,observed 62kDa

location