Anti-IREB2 antibody

Product Name Anti-IREB2 antibody

Catalog No PAab04384

Packing 100ug

Form liquid

Alternative Name

Purification Immunogen affinity purified

Purity 95% as determined by SDS-PAGE

Host Rabbit

Isotype IgG

Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)

Background/ FUNCTION

RNA-binding protein that binds to iron-responsive elements (IRES), which are stem-loop structures found in the 5'- UTR of ferritin, and delta aminolevulinic acid synthase mRNAs, and in the 3'-UTR of transferrin receptor mRNA. Binding to the IRE element in ferritin results in the repression of its mRNA translation. Binding of the protein to the transferrin receptor mRNA inhibits the degradation of this otherwise rapidly degraded mRNA.

Immunogen iron-responsive element binding protein 2

Specificity Human, Mouse

Tested Application ELISA,WB,IF

Recommended dilution

IHC use

WB use

Protein Information

Gene ID3658

Uniprot ID P48200

Calculated MW

location