Anti-IVNS1ABP antibody

Product Name Anti-IVNS1ABP antibody

Catalog No PAab04428

Packing 100ug

Form liquid

Alternative Name ARA3 antibody, FLARA3 antibody, KIAA0850 antibody, NS1 antibody, NS1BP

Purification Immunogen affinity purified

Purity 95% as determined by SDS-PAGE

Host Rabbit

Isotype IgG

Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)

Background/ FUNCTION

Plays a role in cell division and in the dynamic organization of the actin skeleton as a stabilizer of actin filaments by association with F-actin through Kelch repeats. Protects cells from cell death induced by actin destabilization; Protects neurons from dendritic spines and actin filaments damage induced by the actin-destabilizing cytochalasin B when overexpressed. Activates Erk signaling pathway when overexpressed in cultured cell lines (By similarity). May be a component of the cellular splicing machinery with a role in pre-mRNA splicing; may mediate the inhibition of splicing by NS/influenza virus NS1A protein. Functions as modifier of the AHR/Aryl hydrocarbon receptor pathway increasing the concentration of AHR available to activate transcription.

Immunogen influenza virus NS1A binding protein

Specificity Human,Mouse ,Rat

Tested Application ELISA,WB,IHC

Recommended dilution

IHC use

Immunohistochemistry of paraffin-embedded human kidney usingIVNS1ABP antibody at dilution of 1:100

WB use

mouse heart tissue were subjected to SDS PAGE followed by western blot with PAab04428(IVNS1ABP antibody) at dilution of 1:800

Protein Information

Gene ID10625

Uniprot ID Q9Y6Y0

Calculated MW

location