Anti-MCM5 antibody

Product Name Anti-MCM5 antibody

Catalog No PAab05060

Packing 100ug

Form liquid

Alternative Name CDC46

Purification Immunogen affinity purified

Purity 95% as determined by SDS-PAGE

Host Rabbit

Isotype IgG

Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)

Background/ FUNCTION

Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity (By similarity). Interacts with MCMBP.

Immunogen minichromosome maintenance complex component 5

Specificity Human,Mouse ,Rat

Tested Application ELISA,WB,IHC,IP

Recommended dilution

IHC use

Immunohistochemistry of paraffin-embedded human lymphoma usingMCM5 antibody at dilution of 1:100

WB use

Jurkat cells were subjected to SDS PAGE followed by western blot with PAab05060(MCM5 antibody) at dilution of 1:500

Protein Information

Gene ID4174

Uniprot ID P33992

Calculated MW

location