Anti-MRAP2 antibody

Product Name Anti-MRAP2 antibody

Catalog No PAab05304

Packing 100ug

Form liquid

Alternative Name C6orf117

Purification Immunogen affinity purified

Purity 95% as determined by SDS-PAGE

Host Rabbit

Isotype IgG

Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)

Background/ FUNCTION

Modulator of melanocortin receptor 4 (MC4R), a receptor involved in energy homeostasis. Plays a central role in the control of energy homeostasis and body weight regulation by increasing ligand-sensitivity of MC4R and MC4R-mediated generation of cAMP (By similarity). May also act as a negative regulator of MC2R: competes with MRAP for binding to MC2R and impairs the binding of corticotropin (ACTH) to MC2R. May also regulate activity of other melanocortin receptors (MC1R, MC3R and MC5R); however, additional evidences are required in vivo.

Immunogen melanocortin 2 receptor accessory protein 2

Specificity Human, Mouse ,Rat

Tested Application ELISA,IHC

Recommended dilution

IHC use

Immunohistochemical of paraffin-embedded human brain using anti-MRAP2 antibody at dilution of 1:50

Protein Information

Gene ID112609

Uniprot ID Q96G30

Calculated MW 24 kDa

location Endoplasmic reticulum;Plasma membrane