Anti-NHP2 antibody

Product Name Anti-NHP2 antibody

Catalog No PAab05727

Packing 100ug

Form liquid

Alternative Name NOLA2

Purification Immunogen affinity purified

Purity 95% as determined by SDS-PAGE

Host Rabbit

Isotype IgG

Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)

Background/ FUNCTION

Required for ribosome biogenesis and telomere maintenance. Part of the H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP) complex, which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Each rRNA can contain up to 100 pseudouridine ("psi") residues, which may serve to stabilize the conformation of rRNAs. May also be required for correct processing or intranuclear trafficking of TERC, the RNA component of the telomerase reverse transcriptase (TERT) holoenzyme.

Immunogen NHP2 ribonucleoprotein homolog (yeast)

Specificity Human,Mouse ,Rat

Tested Application ELISA,WB,IHC,IF,IP

Recommended dilution

IHC use

Immunohistochemistry of paraffin-embedded human prostate cancer usingNHP2 antibody at dilution of 1:100

WB use

A375 cells were subjected to SDS PAGE followed by western blot with PAab05727(NHP2 antibody) at dilution of 1:300

Protein Information

Gene ID55651

Uniprot ID Q9NX24

Calculated MW

location