Anti-NLRP2 antibody
Product Name Anti-NLRP2 antibody
Catalog No PAab05758
Packing 100ug
Form liquid
Alternative Name NALP2 antibody, NBS1 antibody, PAN1 antibody, PYPAF2
Purification Immunogen affinity purified
Purity 95% as determined by SDS-PAGE
Host Rabbit
Isotype IgG
Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)
Background/ FUNCTION
Suppresses TNF- and CD40-induced NFKB1 activity at the level of the IKK complex, by inhibiting NFKBIA degradation induced by TNF. When associated with PYCARD, activates CASP1, leading to the secretion of mature proinflammatory cytokine IL1B. May be a component of the inflammasome, a protein complex which also includes PYCARD, CARD8 and CASP1 and whose function would be the activation of proinflammatory caspases.
Immunogen NLR family, pyrin domain containing 2
Specificity Human, Mouse
Tested Application ELISA,WB,IHC
Recommended dilution
IHC use
Immunohistochemistry of paraffin-embedded human placenta usingNLRP2 antibody at dilution of 1:50
WB use
A549 cells were subjected to SDS PAGE followed by western blot with PAab05758(NLRP2 antibody) at dilution of 1:500
Protein Information
Gene ID55655
Uniprot ID Q9NX02
Calculated MW
location