Anti-NLRP2 antibody

Product Name Anti-NLRP2 antibody

Catalog No PAab05758

Packing 100ug

Form liquid

Alternative Name NALP2 antibody, NBS1 antibody, PAN1 antibody, PYPAF2

Purification Immunogen affinity purified

Purity 95% as determined by SDS-PAGE

Host Rabbit

Isotype IgG

Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)

Background/ FUNCTION

Suppresses TNF- and CD40-induced NFKB1 activity at the level of the IKK complex, by inhibiting NFKBIA degradation induced by TNF. When associated with PYCARD, activates CASP1, leading to the secretion of mature proinflammatory cytokine IL1B. May be a component of the inflammasome, a protein complex which also includes PYCARD, CARD8 and CASP1 and whose function would be the activation of proinflammatory caspases.

Immunogen NLR family, pyrin domain containing 2

Specificity Human, Mouse

Tested Application ELISA,WB,IHC

Recommended dilution

IHC use

Immunohistochemistry of paraffin-embedded human placenta usingNLRP2 antibody at dilution of 1:50

WB use

A549 cells were subjected to SDS PAGE followed by western blot with PAab05758(NLRP2 antibody) at dilution of 1:500

Protein Information

Gene ID55655

Uniprot ID Q9NX02

Calculated MW

location