Anti-NOTCH3 antibody
Product Name Anti-NOTCH3 antibody
Catalog No PAab05800
Packing 100ug
Form liquid
Alternative Name
Purification Immunogen affinity purified
Purity 95% as determined by SDS-PAGE
Host Rabbit
Isotype IgG
Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)
Background/ FUNCTION
Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs (By similarity).
Immunogen Notch homolog 3 (Drosophila)
Specificity Human,Mouse ,Rat
Tested Application ELISA,WB,IHC,IP
Recommended dilution
IHC use
Immunohistochemistry of paraffin-embedded human lung cancer tissue slide using NOTCH3 Antibody at dilution of 1:200 heat mediated antigen retrieved with Tris-EDTA bufferpH9).
WB use
COLO 320 cells were subjected to SDS PAGE followed by western blot with PAab05800(NOTCH3 antibody) at dilution of 1:500
Protein Information
Gene ID4854
Uniprot ID Q9UM47
Calculated MW
location