Anti-NPHP5,IQCB1 antibody

Product Name Anti-NPHP5,IQCB1 antibody

Catalog No PAab05818

Packing 100ug

Form liquid

Alternative Name IQ motif containing B1 antibody, IQCB1 antibody, KIAA0036 antibody, Nephrocystin 5 antibody, NPHP5 antibody, PIQ antibody, SLSN5

Purification Immunogen affinity purified

Purity 95% as determined by SDS-PAGE

Host Rabbit

Isotype IgG

Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)

Background/ FUNCTION

IQCB1, also known as NPHP5, is a nephrocystin protein that interacts with calmodulin and the retinitis pigmentosa GTPase regulator protein. It has a central coiled-coil region and two calmodulin-binding IQ domains. Localized to the primary cilia of renal epithelial cells and connecting cilia of photoreceptor cells, IQCB1 is thought to play a role in ciliary function. Mutations in this gene result in Senior-Loken syndrome type 5, a juvenile disorder characterized by defects in the waste filtering system of the kidney, as well as retinal degradation.

Immunogen IQ motif containing B1

Specificity Human,Mouse ,Rat

Tested Application ELISA,IF

Recommended dilution IF : 1:10-1:100

IHC use

WB use

Protein Information

Gene ID9657

Uniprot ID Q15051

Calculated MW 69 kDa

location