Anti-NUDT21 antibody

Product Name Anti-NUDT21 antibody

Catalog No PAab05904

Packing 100ug

Form liquid

Alternative Name CFIM25 antibody, CPSF25 antibody, CPSF5

Purification Immunogen affinity purified

Purity 95% as determined by SDS-PAGE

Host Rabbit

Isotype IgG

Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)

Background/ FUNCTION

Component of the cleavage factor Im (CFIm) complex that plays a key role in pre-mRNA 3'-processing. Involved in association with CPSF6 or CPSF7 in pre-MRNA 3'-end poly(A) site cleavage and poly(A) addition. NUDT21/CPSF5 binds to cleavage and polyadenylation RNA substrates. The homodimer mediates simultaneous sequence-specific recognition of two 5'-UGUA-3' elements within the pre-mRNA. Binds to, but does not hydrolyze mono- and di-adenosine nucleotides. May have a role in mRNA export.

Immunogen nudix (nucleoside diphosphate linked moiety X)-type motif 21

Specificity Human,Mouse ,Rat

Tested Application ELISA,WB,IHC,IF,IP

Recommended dilution

IHC use

Immunohistochemistry of paraffin-embedded human placenta usingNUDT21 antibody at dilution of 1:50

WB use

human brain tissue were subjected to SDS PAGE followed by western blot with PAab05904(NUDT21 antibody) at dilution of 1:500

Protein Information

Gene ID11051

Uniprot ID O43809

Calculated MW

location