Anti-NUMB antibody

Product Name Anti-NUMB antibody

Catalog No PAab05914

Packing 100ug

Form liquid

Alternative Name

Purification Immunogen affinity purified

Purity 95% as determined by SDS-PAGE

Host Rabbit

Isotype IgG

Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)

Background/ FUNCTION

Plays a role in the process of neurogenesis. Required throughout embryonic neurogenesis to maintain neural progenitor cells, also called radial glial cells (RGCs), by allowing their daughter cells to choose progenitor over neuronal cell fate. Not required for the proliferation of neural progenitor cells before the onset of neurogenesis. Also involved postnatally in the subventricular zone (SVZ) neurogenesis by regulating SVZ neuroblasts survival and ependymal wall integrity. May also mediate local repair of brain ventricular wall damage.

Immunogen numb homolog (Drosophila)

Specificity Human, Mouse

Tested Application ELISA,WB,IHC,IF,FC

Recommended dilution

IHC use

Immunohistochemistry of paraffin-embedded human brain usingNUMB antibody at dilution of 1:100

WB use

mouse brain tissue were subjected to SDS PAGE followed by western blot with PAab05914(NUMB antibody) at dilution of 1:800

Protein Information

Gene ID8650

Uniprot ID P49757

Calculated MW

location