Anti-NUP85 antibody
Product Name Anti-NUP85 antibody
Catalog No PAab05929
Packing 100ug
Form liquid
Alternative Name NUP75 antibody, PCNT1
Purification Immunogen affinity purified
Purity 95% as determined by SDS-PAGE
Host Rabbit
Isotype IgG
Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)
Background/ FUNCTION
Essential component of the nuclear pore complex (NPC) that seems to be required for NPC assembly and maintenance. As part of the NPC Nup107-160 subcomplex plays a role in RNA export and in tethering NUP98/Nup98 and NUP153 to the nucleus. The Nup107-160 complex seems to be required for spindle assembly during mitosis. NUP85 is required for membrane clustering of CCL2- activated CCR2. Seems to be involved in CCR2-mediated chemotaxis of monocytes and may link activated CCR2 to the phosphatidyl- inositol 3-kinase-Rac-lammellipodium protrusion cascade.
Immunogen nucleoporin 85kDa
Specificity Human, Mouse
Tested Application ELISA,WB,IHC,IF
Recommended dilution
IHC use
Immunohistochemistry of paraffin-embedded human stomach usingNUP85 antibody at dilution of 1:50
WB use
mouse lung tissue were subjected to SDS PAGE followed by western blot with PAab05929(NUP85 antibody) at dilution of 1:400
Protein Information
Gene ID79902
Uniprot ID Q9BW27
Calculated MW
location