Anti-NUP85 antibody

Product Name Anti-NUP85 antibody

Catalog No PAab05929

Packing 100ug

Form liquid

Alternative Name NUP75 antibody, PCNT1

Purification Immunogen affinity purified

Purity 95% as determined by SDS-PAGE

Host Rabbit

Isotype IgG

Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)

Background/ FUNCTION

Essential component of the nuclear pore complex (NPC) that seems to be required for NPC assembly and maintenance. As part of the NPC Nup107-160 subcomplex plays a role in RNA export and in tethering NUP98/Nup98 and NUP153 to the nucleus. The Nup107-160 complex seems to be required for spindle assembly during mitosis. NUP85 is required for membrane clustering of CCL2- activated CCR2. Seems to be involved in CCR2-mediated chemotaxis of monocytes and may link activated CCR2 to the phosphatidyl- inositol 3-kinase-Rac-lammellipodium protrusion cascade.

Immunogen nucleoporin 85kDa

Specificity Human, Mouse

Tested Application ELISA,WB,IHC,IF

Recommended dilution

IHC use

Immunohistochemistry of paraffin-embedded human stomach usingNUP85 antibody at dilution of 1:50

WB use

mouse lung tissue were subjected to SDS PAGE followed by western blot with PAab05929(NUP85 antibody) at dilution of 1:400

Protein Information

Gene ID79902

Uniprot ID Q9BW27

Calculated MW

location