Anti-NUS1 antibody
Product Name Anti-NUS1 antibody
Catalog No PAab05937
Packing 100ug
Form liquid
Alternative Name C6orf68 antibody, NGBR
Purification Immunogen affinity purified
Purity 95% as determined by SDS-PAGE
Host Rabbit
Isotype IgG
Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)
Background/ FUNCTION
With DHDDS, forms the dehydrodolichyl diphosphate synthase (DDS) complex, an essential component of the dolichol monophosphate (Dol-P) biosynthetic machinery. Adds multiple copies of isopentenyl pyrophosphate (IPP) to farnesyl pyrophosphate (FPP) to produce dehydrodolichyl diphosphate (Dedol-PP), a precusrosor of dolichol which is utilized as a sugar carrier in protein glycosylation in the endoplasmic reticulum (ER). Regulates the glycosylation and stability of nascent NPC2, thereby promoting trafficking of LDL-derived cholesterol. Acts as a specific receptor for the N-terminus of Nogo-B, a neural and cardiovascular regulator.
Immunogen nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae)
Specificity Human,Mouse ,Rat
Tested Application ELISA,WB
Recommended dilution
IHC use
WB use
Protein Information
Gene ID116150
Uniprot ID Q96E22
Calculated MW
location