Anti-NUS1 antibody

Product Name Anti-NUS1 antibody

Catalog No PAab05937

Packing 100ug

Form liquid

Alternative Name C6orf68 antibody, NGBR

Purification Immunogen affinity purified

Purity 95% as determined by SDS-PAGE

Host Rabbit

Isotype IgG

Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)

Background/ FUNCTION

With DHDDS, forms the dehydrodolichyl diphosphate synthase (DDS) complex, an essential component of the dolichol monophosphate (Dol-P) biosynthetic machinery. Adds multiple copies of isopentenyl pyrophosphate (IPP) to farnesyl pyrophosphate (FPP) to produce dehydrodolichyl diphosphate (Dedol-PP), a precusrosor of dolichol which is utilized as a sugar carrier in protein glycosylation in the endoplasmic reticulum (ER). Regulates the glycosylation and stability of nascent NPC2, thereby promoting trafficking of LDL-derived cholesterol. Acts as a specific receptor for the N-terminus of Nogo-B, a neural and cardiovascular regulator.

Immunogen nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae)

Specificity Human,Mouse ,Rat

Tested Application ELISA,WB

Recommended dilution

IHC use

WB use

Protein Information

Gene ID116150

Uniprot ID Q96E22

Calculated MW

location