Anti-OFD1 antibody

Product Name Anti-OFD1 antibody

Catalog No PAab05975

Packing 100ug

Form liquid

Alternative Name CXorf5

Purification Immunogen affinity purified

Purity 95% as determined by SDS-PAGE

Host Rabbit

Isotype IgG

Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)

Background/ FUNCTION

Component of the centrioles controlling mother and daughter centrioles length. Recruits to the centriole IFT88 and centriole distal appendage-specific proteins including CEP164. Involved in the biogenesis of the cilium, a centriole-associated function. The cilium is a cell surface projection found in many vertebrate cells required to transduce signals important for development and tissue homeostasis. Plays an important role in development by regulating Wnt signaling and the specification of the left-right axis. Only OFD1 localized at the centriolar satellites is removed by autophagy, which is an important step in the ciliogenesis regulation (By similarity).

Immunogen oral-facial-digital syndrome 1

Specificity Human

Tested Application ELISA,IHC,WB

Recommended dilution

IHC use

Immunohistochemistry of paraffin-embedded human brain slide using OFD1 Antibody at dilution of 1:50

WB use

HeLa cells were subjected to SDS PAGE followed by western blot with PAab05975(OFD1 antibody) at dilution of 1:500

Protein Information

Gene ID8481

Uniprot ID O75665

Calculated MW

location