Anti-OMA1 antibody

Product Name Anti-OMA1 antibody

Catalog No PAab05991

Packing 100ug

Form liquid

Alternative Name MPRP1

Purification Immunogen affinity purified

Purity 95% as determined by SDS-PAGE

Host Rabbit

Isotype IgG

Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)

Background/ FUNCTION

Metalloprotease that is part of the quality control system in the inner membrane of mitochondria. Following stress conditions that induce loss of mitochondrial membrane potential, mediates cleavage of OPA1 at S1 position, leading to OPA1 inactivation and negative regulation of mitochondrial fusion. May also cleave UQCC3 under these conditions. Its role in mitochondrial quality control is essential for regulating lipid metabolism as well as to maintain body temperature and energy expenditure under cold-stress conditions.

Immunogen OMA1 homolog, zinc metallopeptidase (S. cerevisiae)

Specificity Human, Mouse ,Rat

Tested Application ELISA,WB

Recommended dilution

IHC use

WB use

Protein Information

Gene ID115209

Uniprot ID Q96E52

Calculated MW

location