Anti-PA2G4 antibody
Product Name Anti-PA2G4 antibody
Catalog No PAab06093
Packing 100ug
Form liquid
Alternative Name EBP1
Purification Immunogen affinity purified
Purity 95% as determined by SDS-PAGE
Host Rabbit
Isotype IgG
Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)
Background/ FUNCTION
May play a role in a ERBB3-regulated signal transduction pathway. Seems be involved in growth regulation. Acts a corepressor of the androgen receptor (AR) and is regulated by the ERBB3 ligand neuregulin-1/heregulin (HRG). Inhibits transcription of some E2F1-regulated promoters, probably by recruiting histone acetylase (HAT) activity. Binds RNA. Associates with 28S, 18S and 5.8S mature rRNAs, several rRNA precursors and probably U3 small nucleolar RNA. May be involved in regulation of intermediate and late steps of rRNA processing. May be involved in ribosome assembly. Mediates cap-independent translation of specific viral IRESs (internal ribosomal entry site) (By similarity). Regulates cell proliferation, differentiation, and survival. Isoform 1 suppresses apoptosis whereas isoform 2 promotes cell differentiation (By similarity).
Immunogen proliferation-associated 2G4, 38kDa
Specificity Human,Mouse ,Rat
Tested Application ELISA,WB,IHC,IF,FC
Recommended dilution
IHC use
Immunohistochemistry of paraffin-embedded human breast cancer usingPA2G4 antibody at dilution of 1:100
WB use
Jurkat cells were subjected to SDS PAGE followed by western blot with PAab06093(PA2G4 antibody) at dilution of 1:2000
Protein Information
Gene ID5036
Uniprot ID Q9UQ80
Calculated MW
location