Anti-PAK6 antibody
Product Name Anti-PAK6 antibody
Catalog No PAab06124
Packing 100ug
Form liquid
Alternative Name PAK5
Purification Immunogen affinity purified
Purity 95% as determined by SDS-PAGE
Host Rabbit
Isotype IgG
Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)
Background/ FUNCTION
Serine/threonine protein kinase that plays a role in the regulation of gene transcription. The kinase activity is induced by various effectors including AR or MAP2K6/MAPKK6. Phosphorylates the DNA-binding domain of androgen receptor/AR and thereby inhibits AR-mediated transcription. Inhibits also ESR1-mediated transcription. May play a role in cytoskeleton regulation by interacting with IQGAP1. May protect cells from apoptosis through phosphorylation of BAD.
Immunogen p21 protein (Cdc42/Rac)-activated kinase 6
Specificity Human,Mouse ,Rat
Tested Application ELISA,WB,IHC
Recommended dilution
IHC use
Immunohistochemistry of paraffin-embedded human prostate cancer usingPAK6 antibody at dilution of 1:100
WB use
PC-3 cells were subjected to SDS PAGE followed by western blot with PAab06124(PAK6 antibody) at dilution of 1:400
Protein Information
Gene ID56924
Uniprot ID Q9NQU5
Calculated MW
location