Anti-PAK6 antibody

Product Name Anti-PAK6 antibody

Catalog No PAab06124

Packing 100ug

Form liquid

Alternative Name PAK5

Purification Immunogen affinity purified

Purity 95% as determined by SDS-PAGE

Host Rabbit

Isotype IgG

Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)

Background/ FUNCTION

Serine/threonine protein kinase that plays a role in the regulation of gene transcription. The kinase activity is induced by various effectors including AR or MAP2K6/MAPKK6. Phosphorylates the DNA-binding domain of androgen receptor/AR and thereby inhibits AR-mediated transcription. Inhibits also ESR1-mediated transcription. May play a role in cytoskeleton regulation by interacting with IQGAP1. May protect cells from apoptosis through phosphorylation of BAD.

Immunogen p21 protein (Cdc42/Rac)-activated kinase 6

Specificity Human,Mouse ,Rat

Tested Application ELISA,WB,IHC

Recommended dilution

IHC use

Immunohistochemistry of paraffin-embedded human prostate cancer usingPAK6 antibody at dilution of 1:100

WB use

PC-3 cells were subjected to SDS PAGE followed by western blot with PAab06124(PAK6 antibody) at dilution of 1:400

Protein Information

Gene ID56924

Uniprot ID Q9NQU5

Calculated MW

location