Anti-PAWR antibody
Product Name Anti-PAWR antibody
Catalog No PAab06166
Packing 100ug
Form liquid
Alternative Name PAR4
Purification Immunogen affinity purified
Purity 95% as determined by SDS-PAGE
Host Rabbit
Isotype IgG
Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)
Background/ FUNCTION
Pro-apoptopic protein capable of selectively inducing apoptosis in cancer cells, sensitizing the cells to diverse apoptotic stimuli and causing regression of tumors in animal models. Induces apoptosis in certain cancer cells by activation of the Fas prodeath pathway and coparallel inhibition of NF-kappa-B transcriptional activity. Inhibits the transcriptional activation and augments the transcriptional repression mediated by WT1. Down- regulates the anti-apoptotic protein BCL2 via its interaction with WT1. Seems also to be a transcriptional repressor by itself. May be directly involved in regulating the amyloid precursor protein (APP) cleavage activity of BACE1.
Immunogen PRKC, apoptosis, WT1, regulator
Specificity Human,Mouse ,Rat
Tested Application ELISA,WB,IHC
Recommended dilution
IHC use
Immunohistochemistry of paraffin-embedded human kidney slide using PAWR Antibody at dilution of 1:50
WB use
mouse heart tissue were subjected to SDS PAGE followed by western blot with PAab06166(PAWR antibody) at dilution of 1:400
Protein Information
Gene ID5074
Uniprot ID Q96IZ0
Calculated MW
location