Anti-PDK3 antibody
Product Name Anti-PDK3 antibody
Catalog No PAab06278
Packing 100ug
Form liquid
Alternative Name PDHK3
Purification Immunogen affinity purified
Purity 95% as determined by SDS-PAGE
Host Rabbit
Isotype IgG
Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)
Background/ FUNCTION
Inhibits pyruvate dehydrogenase activity by phosphorylation of the E1 subunit PDHA1, and thereby regulates glucose metabolism and aerobic respiration. Can also phosphorylate PDHA2. Decreases glucose utilization and increases fat metabolism in response to prolonged fasting, and as adaptation to a high-fat diet. Plays a role in glucose homeostasis and in maintaining normal blood glucose levels in function of nutrient levels and under starvation. Plays a role in the generation of reactive oxygen species.
Immunogen pyruvate dehydrogenase kinase, isozyme 3
Specificity Human, Mouse
Tested Application ELISA,WB,IHC
Recommended dilution
IHC use
Immunohistochemistry of paraffin-embedded human heart slide using PDK3 Antibody at dilution of 1:50
WB use
mouse heart tissue were subjected to SDS PAGE followed by western blot with PAab06278(PDK3 antibody) at dilution of 1:1000
Protein Information
Gene ID5165
Uniprot ID Q15120
Calculated MW
location