Anti-PRKACB antibody
Product Name Anti-PRKACB antibody
Catalog No PAab06778
Packing 100ug
Form liquid
Alternative Name
Purification Immunogen affinity purified
Purity 95% as determined by SDS-PAGE
Host Rabbit
Isotype IgG
Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)
Background/ FUNCTION
Mediates cAMP-dependent signaling triggered by receptor binding to GPCRs. PKA activation regulates diverse cellular processes such as cell proliferation, the cell cycle, differentiation and regulation of microtubule dynamics, chromatin condensation and decondensation, nuclear envelope disassembly and reassembly, as well as regulation of intracellular transport mechanisms and ion flux. Regulates the abundance of compartmentalized pools of its regulatory subunits through phosphorylation of PJA2 which binds and ubiquitinates these subunits, leading to their subsequent proteolysis.
Immunogen protein kinase, cAMP-dependent, catalytic, beta
Specificity Human,Mouse ,Rat
Tested Application ELISA,WB,IHC,IF,IP
Recommended dilution
IHC use
Immunohistochemistry of paraffin-embedded human medulloblastoma usingPRKACB antibody at dilution of 1:50
WB use
HT-1080 cells were subjected to SDS PAGE followed by western blot with PAab06778(PRKACB antibody) at dilution of 1:1000
Protein Information
Gene ID5567
Uniprot ID P22694
Calculated MW
location