Anti-PSMB5 antibody

Product Name Anti-PSMB5 antibody

Catalog No PAab06874

Packing 100ug

Form liquid

Alternative Name LMPX antibody, MB1 antibody, X

Purification Immunogen affinity purified

Purity 95% as determined by SDS-PAGE

Host Rabbit

Isotype IgG

Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)

Background/ FUNCTION

The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. This unit is responsible of the chymotrypsin-like activity of the proteasome and is one of the principal target of the proteasome inhibitor bortezomib. May catalyze basal processing of intracellular antigens. Plays a role in the protection against oxidative damage through the Nrf2-ARE pathway (By similarity).

Immunogen proteasome (prosome, macropain) subunit, beta type, 5

Specificity Human,Mouse ,Rat

Tested Application ELISA,WB,IHC,IF

Recommended dilution

IHC use

Immunohistochemistry of paraffin-embedded human breast cancer usingPSMB5 antibody at dilution of 1:50

WB use

L02 cells were subjected to SDS PAGE followed by western blot with PAab06874(PSMB5 antibody) at dilution of 1:1000

Protein Information

Gene ID5693

Uniprot ID P28074

Calculated MW

location