Anti-PTPMT1 antibody

Product Name Anti-PTPMT1 antibody

Catalog No PAab06931

Packing 100ug

Form liquid

Alternative Name MOSP antibody, PLIP

Purification Immunogen affinity purified

Purity 95% as determined by SDS-PAGE

Host Rabbit

Isotype IgG

Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)

Background/ FUNCTION

Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG). PGP is an essential intermediate in the biosynthetic pathway of cardiolipin, a mitochondrial-specific phospholipid regulating the membrane integrity and activities of the organelle. Has also been shown to display phosphatase activity toward phosphoprotein substrates, specifically mediates dephosphorylation of mitochondrial proteins, thereby playing an essential role in ATP production. Has probably a preference for proteins phosphorylated on Ser and/or Thr residues compared to proteins phosphorylated on Tyr residues. Probably involved in regulation of insulin secretion in pancreatic beta cells (By similarity).

Immunogen protein tyrosine phosphatase, mitochondrial 1

Specificity Human, Mouse ,Rat

Tested Application ELISA,WB,IHC

Recommended dilution

IHC use

Immunohistochemistry of paraffin-embedded human pancreas cancer usingPTPMT1 antibody at dilution of 1:50

WB use

mouse pancreas tissue were subjected to SDS PAGE followed by western blot with PAab06931(PTPMT1 antibody) at dilution of 1:300

Protein Information

Gene ID114971

Uniprot ID Q8WUK0

Calculated MW

location