Anti-RAB12 antibody

Product Name Anti-RAB12 antibody

Catalog No PAab06995

Packing 100ug

Form liquid

Alternative Name

Purification Immunogen affinity purified

Purity 95% as determined by SDS-PAGE

Host Rabbit

Isotype IgG

Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)

Background/ FUNCTION

The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. That Rab may play a role in protein transport from recycling endosomes to lysosomes regulating, for instance, the degradation of the transferrin receptor. Involved in autophagy (By similarity).

Immunogen RAB12, member RAS oncogene family

Specificity Human

Tested Application ELISA,WB,IHC,IP

Recommended dilution

IHC use

Immunohistochemistry of paraffin-embedded human liver usingRAB12 antibody at dilution of 1:100

WB use

HeLa cells were subjected to SDS PAGE followed by western blot with PAab06995(RAB12 antibody) at dilution of 1:500

Protein Information

Gene ID201475

Uniprot ID Q6IQ22

Calculated MW

location