Anti-RAB14 antibody

Product Name Anti-RAB14 antibody

Catalog No PAab06996

Packing 100ug

Form liquid

Alternative Name

Purification Immunogen affinity purified

Purity 95% as determined by SDS-PAGE

Host Rabbit

Isotype IgG

Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)

Background/ FUNCTION

Involved in membrane trafficking between the Golgi complex and endosomes during early embryonic development. Regulates the Golgi to endosome transport of FGFR-containing vesicles during early development, a key process for developing basement membrane and epiblast and primitive endoderm lineages during early postimplantation development. May act by modulating the kinesin KIF16B-cargo association to endosomes (By similarity). Regulates, together with its guanine nucleotide exchange factor DENND6A, the specific endocytic transport of ADAM10, N- cadherin/CDH2 shedding and cell-cell adhesion.

Immunogen RAB14, member RAS oncogene family

Specificity Human,Mouse ,Rat

Tested Application ELISA,WB,IHC

Recommended dilution

IHC use

Immunohistochemistry of paraffin-embedded human liver cancer tissue slide using RAB14 Antibody at dilution of 1:50

WB use

human brain tissue were subjected to SDS PAGE followed by western blot with PAab06996(RAB14 antibody) at dilution of 1:500

Protein Information

Gene ID51552

Uniprot ID P61106

Calculated MW

location