Anti-RAN antibody
Product Name Anti-RAN antibody
Catalog No PAab07100
Packing 100ug
Form liquid
Alternative Name ARA24
Purification Immunogen affinity purified
Purity 95% as determined by SDS-PAGE
Host Rabbit
Isotype IgG
Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)
Background/ FUNCTION
GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle (By similarity). The complex with BIRC5/ survivin plays a role in mitotic spindle formation by serving as a physical scaffold to help deliver the RAN effector molecule TPX2 to microtubules. Acts as a negative regulator of the kinase activity of VRK1 and VRK2. Enhances AR-mediated transactivation. Transactivation decreases as the poly-Gln length within AR increases.
Immunogen RAN, member RAS oncogene family
Specificity Human,Mouse ,Rat
Tested Application ELISA,IHC,IF,IP,WB
Recommended dilution
IHC use
Immunohistochemistry of paraffin-embedded human breast cancer tissue slide using RAN Antibody at dilution of 1:50
WB use
HEK-293 cells were subjected to SDS PAGE followed by western blot with PAab07100( RAN Antibody) at dilution of 1:1000
Protein Information
Gene ID5901
Uniprot ID P62826
Calculated MW
location