Anti-RASIP1 antibody

Product Name Anti-RASIP1 antibody

Catalog No PAab07134

Packing 100ug

Form liquid

Alternative Name

Purification Immunogen affinity purified

Purity 95% as determined by SDS-PAGE

Host Rabbit

Isotype IgG

Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)

Background/ FUNCTION

Required for the proper formation of vascular structures that develop via both vasculogenesis and angiogenesis. Acts as a critical and vascular-specific regulator of GTPase signaling, cell architecture, and adhesion, which is essential for endothelial cell morphogenesis and blood vessel tubulogenesis. Regulates the activity of Rho GTPases in part by recruiting ARHGAP29 and suppressing RhoA signaling and dampening ROCK and MYH9 activities in endothelial cells (By similarity). May act as effector for Golgi-bound HRAS and other Ras-like proteins. May promote HRAS- mediated transformation. Negative regulator of amino acid starvation-induced autophagy.

Immunogen Ras interacting protein 1

Specificity Human,Mouse ,Rat

Tested Application ELISA,WB,IHC,IF

Recommended dilution

IHC use

Immunohistochemistry of paraffin-embedded human lung tissue slide using RASIP1 Antibody at dilution of 1:50

WB use

mouse lung tissue were subjected to SDS PAGE followed by western blot with PAab07134( RASIP1 Antibody) at dilution of 1:300

Protein Information

Gene ID54922

Uniprot ID Q5U651

Calculated MW

location